Light-based control of metabolic flux through assembly of synthetic organelles

May 13th, 2019 by Evan M. Zhao

Light-based control of metabolic flux through assembly of synthetic organelles

Nature Chemical Biology, Published online: 13 May 2019; doi:10.1038/s41589-019-0284-8

Optogenetically controlling the assembly of enzyme clusters enhances product formation and specificity during deoxyviolacein biosynthesis by decreasing concentrations of intermediate metabolites and reducing flux through competing pathways.
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