Yes (again) to local NO

May 22nd, 2020 by Emrah Eroglu

Nature Chemical Biology, Published online: 22 May 2020; doi:10.1038/s41589-020-0552-7

A pair of fluorescent indicator-tagged DNA-duplex scaffolds permit assessments of nitric oxide (NO) production on cell surfaces and in intracellular networks. The application of these nanoprobes indicates formations of local NO signals that might conserve cancer cell integrity.