Engineering AraC to make it responsive to light instead of arabinose

April 26th, 2021 by Edoardo Romano

Nature Chemical Biology, Published online: 26 April 2021; doi:10.1038/s41589-021-00787-6

Engineering of a blue light-inducible AraC dimerization system in E. coli permits light-dependent, rather than arabinose-based, regulation of gene expression from standard PBAD promoters, enabling temporal and spatial control of bacterial systems.