Clearing debris

July 8th, 2019 by Delong Meng

Nature Chemical Biology, Published online: 08 July 2019; doi:10.1038/s41589-019-0320-8

A new small molecule that targets the vacuolar H+-ATPase activates autophagy, inhibits mTORC1 signaling, and displays potential for clearing toxic protein aggregates involved in neurodegenerative diseases.