Antifungal design: The toxicity-resistance yin-yang

June 1st, 2015 by David M Geiser

Nature Chemical Biology 11, 453 (2015). doi:10.1038/nchembio.1838

Author: David M Geiser

A modified amphotericin antifungal that is less toxic to human cells, owing to its increased preference for its fungal ergosterol target versus human cholesterol, can still evade the evolution of resistance.