Chemogenetics defines receptor-mediated functions of short chain free fatty acids

April 15th, 2019 by Daniele Bolognini

Chemogenetics defines receptor-mediated functions of short chain free fatty acids

Chemogenetics defines receptor-mediated functions of short chain free fatty acids, Published online: 15 April 2019; doi:10.1038/s41589-019-0270-1

A chemogenomic approach to explore activity of the free fatty acid receptor FFA2 independently of the related FFA3 shows that FFA2 in differentiated adipocytes and colonic crypt cells in mice is responsible for regulated lipolysis and GLP-1 release.
  • Posted in Nat Chem Biol, Publications
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