Structural basis for persulfide-sensing specificity in a transcriptional regulator

October 26th, 2020 by Daiana A. Capdevila

Nature Chemical Biology, Published online: 26 October 2020; doi:10.1038/s41589-020-00671-9

Structural and kinetic analyses of the transcriptional repressor SqrR in multiple states indicate that its persulfide selectivity is determined by structural frustration in the disulfide form, favoring formation of the tetrasulfide-bridged product.
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