The HaloTag as a general scaffold for far-red tunable chemigenetic indicators

April 1st, 2021 by Claire Deo

Nature Chemical Biology, Published online: 01 April 2021; doi:10.1038/s41589-021-00775-w

Combining the self-labeling HaloTag protein with synthetic environmentally sensitive fluorophores provides a platform for the construction of bright, far-red fluorescent calcium and voltage sensors with tunable photophysical and chemical properties.
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