Unifying principles of bifunctional, proximity-inducing small molecules
March 20th, 2020 by Christopher J. Gerry
Nature Chemical Biology, Published online: 20 March 2020; doi:10.1038/s41589-020-0469-1
This Perspective describes the chemical and biophysical principles common to all bifunctional, proximity-inducing small molecules. It also discusses the underappreciated diversity of their chemical structures and biological mechanisms.