Searching for harmony in transition-metal signaling

September 17th, 2015 by Christopher J Chang

Nature Chemical Biology 11, 744 (2015). doi:10.1038/nchembio.1913

Author: Christopher J Chang

The recent emergence of signaling roles for transition metals presages a broader contribution of these elements beyond their traditional functions as metabolic cofactors. New chemical approaches to identify the sources, targets and physiologies of transition-metal signaling can help expand understanding of the periodic table in a biological context.