A gene signal amplifier platform for monitoring the unfolded protein response

March 9th, 2020 by Carlos A. Origel Marmolejo

Nature Chemical Biology, Published online: 09 March 2020; doi:10.1038/s41589-020-0497-x

Engineering of a synthetic circuit that couples transcriptional and protein turnover regulation to a fluorescent protein readout enables sensitive monitoring and amplification of gene expression signals from the unfolded protein response pathway.
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