Activation of silent biosynthetic gene clusters using transcription factor decoys

December 31st, 2018 by Bin Wang

Activation of silent biosynthetic gene clusters using transcription factor decoys

Activation of silent biosynthetic gene clusters using transcription factor decoys, Published online: 31 December 2018; doi:10.1038/s41589-018-0187-0

Transcription factor decoys, DNA molecules designed to mimic regulatory DNAs and prevent repressors binding to their DNA targets, are used to achieve de-repression of silent biosynthetic gene clusters, resulting in production of new natural products.
  • Posted in Nat Chem Biol, Publications
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