Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth

June 29th, 2021 by Bianca J. Lee

Nature Chemical Biology, Published online: 29 June 2021; doi:10.1038/s41589-021-00843-1

Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
  • Posted in Nat Chem Biol, Publications
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Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth

June 24th, 2021 by Bianca J. Lee

Nature Chemical Biology, Published online: 24 June 2021; doi:10.1038/s41589-021-00813-7

Design of a bivalent inhibitor containing an ATP-competitive moiety and rapamycin-modified FRB binding ligand that selectively inhibits mTORC1 results in potent and durable inhibition of 4EBP1 phosphorylation and cell proliferation in vitro and in vivo.
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