Regulation of apoptosis by an intrinsically disordered region of Bcl-xL
March 5th, 2018 by Ariele Viacava Follis
Regulation of apoptosis by an intrinsically disordered region of Bcl-xL
Regulation of apoptosis by an intrinsically disordered region of Bcl-xL, Published online: 05 March 2018; doi:10.1038/s41589-018-0011-x
Post-translational modification of residues in an intrinsically disordered region of Bcl-XL promotes interactions with its folded core and allosterically reduces affinity for proapoptotic BH3-domain-containing proteins, resulting in apoptosis.