Small-molecule phenotypic screening with stem cells

May 17th, 2017 by Andrei Ursu

Nature Chemical Biology 13, 560 (2017). doi:10.1038/nchembio.2383

Authors: Andrei Ursu, Hans R Schöler & Herbert Waldmann

To fully leverage the potential of human-induced pluripotent stem cells (hiPSCs), improved and standardized reprogramming methods and large-scale collections of hiPSC lines are needed, and the stem cell community must embrace chemical biology methodology for target identification and validation.