Rapid generation of potent antibodies by autonomous hypermutation in yeast

June 24th, 2021 by Alon Wellner

Nature Chemical Biology, Published online: 24 June 2021; doi:10.1038/s41589-021-00832-4

Autonomous hypermutation yeast surface display (AHEAD) mimics the process of somatic hypermutation in animals to enable the rapid in vitro evolution of antibodies, including nanobodies targeting the RBD of SARS-CoV-2.
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