<i>ykkC</i> riboswitches employ an add-on helix to adjust specificity for polyanionic ligands

August 17th, 2018 by Alla Peselis

ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands

<i>ykkC</i> riboswitches employ an add-on helix to adjust specificity for polyanionic ligands, Published online: 17 August 2018; doi:10.1038/s41589-018-0114-4

Structural analysis of PRPP and ppGpp riboswitches reveals that they employ a helical element to create a tunnel for the ligand, whose specificity is determined by the conserved nucleotides forming the tunnel and long-distance contacts.
  • Posted in Nat Chem Biol, Publications
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