Pharmacological convergence reveals a lipid pathway that regulates <i>C. elegans</i> lifespan

March 25th, 2019 by Alice L. Chen

Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan

Pharmacological convergence reveals a lipid pathway that regulates <i>C. elegans</i> lifespan, Published online: 25 March 2019; doi:10.1038/s41589-019-0243-4

Phenotypic screening identifies a small-molecule inhibitor of the C. elegans serine hydrolase FAAH-4 that promotes longevity and identifies the enzyme as the functional homolog of mammalian monoacylglycerol lipase (MAGL).
  • Posted in Nat Chem Biol, Publications
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