A flexible filter maintains a tight grip

March 4th, 2019 by Adrian Gross

A flexible filter maintains a tight grip

A flexible filter maintains a tight grip, Published online: 04 March 2019; doi:10.1038/s41589-019-0248-z

Potassium channels allow the passage of potassium ions across membranes at rates approaching the diffusion limit while maintaining exquisite selectivity between ion species. Single-molecule studies now reveal that the selectivity filter of these proteins transitions between different conformations.