Endosome motility defects revealed at super-resolution in live cells using HIDE probes

February 24th, 2020 by Aarushi Gupta

Nature Chemical Biology, Published online: 24 February 2020; doi:10.1038/s41589-020-0479-z

HIDE probes were developed for long time-lapse imaging of endolysosomes and their dynamics at super-resolution. These probes enabled analyses of endosome motility in primary fibroblasts from patients with Niemann–Pick C with distinct mutations in NPC1.
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